Figure shows a schematic depiction of the serotonin pathway from EC to Biology Diagrams Roughly95%of total body serotonin is released into the gut by intestinal enterochromaffin cells , but serotonin is involved at the very moment that food enters the body. Activation of taste-bud cells on the tongue causes serotonin release onto sensory afferent nerves ( 59 ) that transmit taste information to the CNS.
Serotonin acts as both a neurotransmitter and as a peripheral hormone. However, most 5-HT production occurs in the enterochromaffin (EC) cells of the intestinal mucosa. The gut is the largest endocrine organ in human body, and it produces almost 95% of all the serotonin.
A new map of the brain's serotonin system Biology Diagrams
Serotonin (/ ห s ษr ษ ห t oส n ษช n, ห s ษชษr ษ-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction. [9]Serotonin is produced in the central nervous system (CNS Serotonin, or 5-hydroxytryptamine (5-HT), is a neurotransmitter with an integral physiological role in the human body; it regulates various activities, including behavior, mood, memory, and gastrointestinal homeostasis.[1][2] Serotonin is synthesized in the raphe nuclei of the brainstem and the enterochromaffin cells of the intestinal mucosa.[3][4]
An alternate pathway for serotonin exists in the pineal gland; it converts to melatonin. Serotonin originating from enterochromaffin cells is released into the portal circulation and undergoes rapid elimination from the plasma by way of uptake into platelets and liver metabolism. An estimated 90% of the serotonin in the human body is stored
Serotonin in the Brain: Functions, Effects, and Regulation Biology Diagrams
A serotonin pathway identifies aggregate projections from neurons which synthesize and communicate the monoamine neurotransmitter serotonin. [citation needed] These pathways are relevant to different psychiatric and neurological disorders. [1] [2] [3] Pathways. Pathway Group Origin [4] Projections
